Drug Information
| Drug Generic Name | PYRAZINAMIDE |
| Drug Class | ANTIMYCOBACTRIAL DRUGS |
| Chapter | Infections |
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Indications: tuberculosis in combination with other drugs. Cautions: impaired renal function, diabetes, gout, liver-function tests required, pregnancy. Contra-indications: Porphyria Side Effects: hepatomegaly, hepatotoxicity including fever, anorexia, jaundice, fulminating liver failure; nausea, vomiting, arthralgia, sideroblastic anaemia, urticaria. Dose: by mouth as a single dose, 35 mg/kg daily; max. daily dose, 3g-Alternative dosing schedule, 50 mg/kg three times weekly or 75mg/kg twice weekly. |
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